Acanthosis nigricans
☆ V rezultatih raziskave Stiftung Warentest iz Nemčije leta 2022 je bilo zadovoljstvo potrošnikov z ModelDermom le nekoliko nižje kot s plačanimi telemedicinskimi svetovanji.
Pogosta je pri debelih ljudeh.
References
Acanthosis nigricans je kožna manifestacija osnovne bolezni. Pogosto se pojavi v kožnih gubah, kot so vrat, pazduhe in dimlje, in je videti kot žametno temne lise z nejasnimi robovi. To stanje je običajno povezano s sladkorno boleznijo in insulinsko rezistenco, vendar v redkih primerih lahko kaže na raka v telesu. Lahko se pojavi tudi zaradi hormonskih težav ali jemanja določenih zdravil, kot so steroidi in kontracepcijske tablete.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) je pogosta kožna bolezen, povezana z različnimi zdravstvenimi težavami, kot so insulinska rezistenca, sladkorna bolezen, debelost, nekatere vrste raka, hormonske težave in reakcije na zdravila. Zdravljenje AN se osredotoča na obravnavo osnovnih zdravstvenih težav. Na začetku zdravniki preverijo znake sindroma insulinske rezistence, ki vključuje debelost, visok holesterol, visok krvni tlak in sladkorno bolezen tipa 2. Zdravniki pogosto predpišejo topical retinoids kot prvo izbiro zdravljenja, ki lahko pomaga pri zadebelitvi kože. Vendar morda ne bodo v celoti odpravili temnenja kože. Tudi druge možnosti zdravljenja, kot je salicylic acid, podophyllin, urea, and calcipotriol , potrebujejo pogosto uporabo.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ Vzroki
Običajno se pojavi pri osebah, mlajših od 40 let, lahko je genetsko podedovana in povezana z debelostjo ali endokrinopatijami, kot so hipotiroidizem, akromegalija, bolezen policističnih jajčnikov, inzulinsko odporna sladkorna bolezen ali Cushingova bolezen.
○ Zdravljenje ― OTC zdravila
#40% urea cream